Virology MCQs (Quiz 8) Posted on July 13, 2026Author agropublishers 0 1. In viruses, genome reassortment is only possible in viruses with ____________ Segmented genomes Positive-sense RNA genomes DNA genomes Circular genomes 2. Direct Fluorescent Antibody (DFA) testing is classically used for laboratory diagnosis of __________________ Poliomyelitis Influenza Rabies Human Immunodeficiency Virus (HIV) 3. Which Nobel Prize-winning discovery demonstrated that DNA is the hereditary material in viruses? Griffith’s transformation experiment Avery–MacLeod–McCarty experiment Hershey–Chase experiment Watson and Crick’s DNA model 4. __________________ allow researchers to grow and study viruses that require living host cells to replicate Nutrient broth culture Gram staining Litmus paper testing Cell culture (tissue culture) techniques 5. Which of the following may represent the clinical outcome of a viral infection? Acute self-limiting illness Asymptomatic (subclinical) infection All of these Chronic infection with persistent viral shedding 6. Which technological advance tool most transformed virology in the 21st century? High-throughput genomics and bioinformatics Gram staining Animal inoculation Light microscopy 7. Human papillomavirus causes _________________ or tumor Condyloma acuminatum Cervical cancer Hepatic carcinoma Plantar wart 8. ____________________ viral genome has the same sequence orientation as host mRNA Negative-sense RNA Positive-sense RNA Double-stranded RNA Double-stranded DNA 9. _________________________ is the most commonly used method to detect and quantify viral RNA or DNA in a clinical sample Polymerase chain reaction (PCR) Western blotting Enzyme-linked immunosorbent assay (ELISA) Agar diffusion assay 10. Which viral component primarily determines antigenicity? Envelope lipid Host-cell membrane Surface proteins Genome Loading … Question 1 of 10
