Virology MCQs (Quiz 8) Posted on July 13, 2026Author agropublishers 0 1. Which Nobel Prize-winning discovery demonstrated that DNA is the hereditary material in viruses? Watson and Crick’s DNA model Avery–MacLeod–McCarty experiment Hershey–Chase experiment Griffith’s transformation experiment 2. Which viral component primarily determines antigenicity? Surface proteins Host-cell membrane Envelope lipid Genome 3. Which of the following may represent the clinical outcome of a viral infection? Asymptomatic (subclinical) infection Chronic infection with persistent viral shedding All of these Acute self-limiting illness 4. ____________________ viral genome has the same sequence orientation as host mRNA Double-stranded RNA Negative-sense RNA Double-stranded DNA Positive-sense RNA 5. Direct Fluorescent Antibody (DFA) testing is classically used for laboratory diagnosis of __________________ Influenza Poliomyelitis Human Immunodeficiency Virus (HIV) Rabies 6. Which technological advance tool most transformed virology in the 21st century? Light microscopy Gram staining Animal inoculation High-throughput genomics and bioinformatics 7. __________________ allow researchers to grow and study viruses that require living host cells to replicate Cell culture (tissue culture) techniques Gram staining Nutrient broth culture Litmus paper testing 8. _________________________ is the most commonly used method to detect and quantify viral RNA or DNA in a clinical sample Agar diffusion assay Enzyme-linked immunosorbent assay (ELISA) Western blotting Polymerase chain reaction (PCR) 9. In viruses, genome reassortment is only possible in viruses with ____________ Circular genomes Segmented genomes DNA genomes Positive-sense RNA genomes 10. Human papillomavirus causes _________________ or tumor Condyloma acuminatum Plantar wart Cervical cancer Hepatic carcinoma Loading … Question 1 of 10