Virology MCQs (Quiz 8) Posted on July 13, 2026Author agropublishers 0 1. ____________________ viral genome has the same sequence orientation as host mRNA Double-stranded RNA Negative-sense RNA Positive-sense RNA Double-stranded DNA 2. Which viral component primarily determines antigenicity? Host-cell membrane Surface proteins Envelope lipid Genome 3. __________________ allow researchers to grow and study viruses that require living host cells to replicate Litmus paper testing Gram staining Nutrient broth culture Cell culture (tissue culture) techniques 4. _________________________ is the most commonly used method to detect and quantify viral RNA or DNA in a clinical sample Polymerase chain reaction (PCR) Agar diffusion assay Enzyme-linked immunosorbent assay (ELISA) Western blotting 5. In viruses, genome reassortment is only possible in viruses with ____________ Segmented genomes DNA genomes Circular genomes Positive-sense RNA genomes 6. Direct Fluorescent Antibody (DFA) testing is classically used for laboratory diagnosis of __________________ Human Immunodeficiency Virus (HIV) Rabies Poliomyelitis Influenza 7. Human papillomavirus causes _________________ or tumor Hepatic carcinoma Plantar wart Condyloma acuminatum Cervical cancer 8. Which technological advance tool most transformed virology in the 21st century? High-throughput genomics and bioinformatics Animal inoculation Light microscopy Gram staining 9. Which of the following may represent the clinical outcome of a viral infection? Asymptomatic (subclinical) infection All of these Acute self-limiting illness Chronic infection with persistent viral shedding 10. Which Nobel Prize-winning discovery demonstrated that DNA is the hereditary material in viruses? Watson and Crick’s DNA model Hershey–Chase experiment Avery–MacLeod–McCarty experiment Griffith’s transformation experiment Loading … Question 1 of 10
