Virology MCQs (Quiz 8) Posted on July 13, 2026Author agropublishers 0 1. Which technological advance tool most transformed virology in the 21st century? Animal inoculation Gram staining Light microscopy High-throughput genomics and bioinformatics 2. __________________ allow researchers to grow and study viruses that require living host cells to replicate Nutrient broth culture Cell culture (tissue culture) techniques Litmus paper testing Gram staining 3. _________________________ is the most commonly used method to detect and quantify viral RNA or DNA in a clinical sample Polymerase chain reaction (PCR) Western blotting Agar diffusion assay Enzyme-linked immunosorbent assay (ELISA) 4. Which Nobel Prize-winning discovery demonstrated that DNA is the hereditary material in viruses? Watson and Crick’s DNA model Hershey–Chase experiment Avery–MacLeod–McCarty experiment Griffith’s transformation experiment 5. Direct Fluorescent Antibody (DFA) testing is classically used for laboratory diagnosis of __________________ Influenza Human Immunodeficiency Virus (HIV) Rabies Poliomyelitis 6. In viruses, genome reassortment is only possible in viruses with ____________ Segmented genomes Positive-sense RNA genomes Circular genomes DNA genomes 7. ____________________ viral genome has the same sequence orientation as host mRNA Double-stranded DNA Double-stranded RNA Negative-sense RNA Positive-sense RNA 8. Which viral component primarily determines antigenicity? Genome Host-cell membrane Surface proteins Envelope lipid 9. Which of the following may represent the clinical outcome of a viral infection? Chronic infection with persistent viral shedding Asymptomatic (subclinical) infection Acute self-limiting illness All of these 10. Human papillomavirus causes _________________ or tumor Hepatic carcinoma Cervical cancer Plantar wart Condyloma acuminatum Loading … Question 1 of 10