Virology MCQs (Quiz 8) Posted on July 13, 2026Author agropublishers 0 1. In viruses, genome reassortment is only possible in viruses with ____________ DNA genomes Positive-sense RNA genomes Circular genomes Segmented genomes 2. __________________ allow researchers to grow and study viruses that require living host cells to replicate Cell culture (tissue culture) techniques Gram staining Litmus paper testing Nutrient broth culture 3. Which of the following may represent the clinical outcome of a viral infection? All of these Asymptomatic (subclinical) infection Acute self-limiting illness Chronic infection with persistent viral shedding 4. Human papillomavirus causes _________________ or tumor Condyloma acuminatum Cervical cancer Plantar wart Hepatic carcinoma 5. Which viral component primarily determines antigenicity? Genome Envelope lipid Host-cell membrane Surface proteins 6. Which Nobel Prize-winning discovery demonstrated that DNA is the hereditary material in viruses? Griffith’s transformation experiment Avery–MacLeod–McCarty experiment Watson and Crick’s DNA model Hershey–Chase experiment 7. Direct Fluorescent Antibody (DFA) testing is classically used for laboratory diagnosis of __________________ Human Immunodeficiency Virus (HIV) Poliomyelitis Influenza Rabies 8. _________________________ is the most commonly used method to detect and quantify viral RNA or DNA in a clinical sample Agar diffusion assay Polymerase chain reaction (PCR) Western blotting Enzyme-linked immunosorbent assay (ELISA) 9. Which technological advance tool most transformed virology in the 21st century? Light microscopy Gram staining Animal inoculation High-throughput genomics and bioinformatics 10. ____________________ viral genome has the same sequence orientation as host mRNA Double-stranded DNA Double-stranded RNA Negative-sense RNA Positive-sense RNA Loading … Question 1 of 10
